Iron infusion side effects vary depending on which form is being used. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. (And Injectafer is used to treat IDA.) Back pain. You will need to talk about the benefits and risks to you and the baby. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. And this can lead to anemia, including IDA. A variety of tests can diagnose iron deficiency anemia. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Consult the product instructions and your pharmacist for storage details. Nose or throat irritation. 5 0 obj In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. What is Venofer? Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Mental healthdisorders like depression may requireantidepressantsto treat. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Renal elimination is negligible. However, consuming large amounts of alcohol can actually cause anemia in some people. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Last updated August 20, 2020. intense abdominal pain. One study of just under 5000 HRT users found that 43% were affected. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Find out what health conditions may be a health risk when taken with Venofer Vial Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. . Talk with the doctor. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Learn how to store and discard medical supplies safely. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. wAd**CgI%"nn{Oa[q{r5 Cardiovascular health: Insomnia linked to greater risk of heart attack. Use Venofer as ordered by your doctor. If you have diarrhea while youre taking Injectafer, call your doctor. This medication is given by injection into a vein as directed by your doctor. Check with your pharmacist. The benefit of treating your condition during pregnancy may outweigh any risks. Some may be a better fit for you than others. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Mild side effects of Injectafer can include:*. (IV iron is absorbed by the body more rapidly than oral iron.) If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. It is important to get each dose of this medication as scheduled. If either is present, do not use the liquid. Call your doctor right away if you have serious side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. dizziness. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Use of the term female in this article refers to sex assigned at birth. These nutrients include iron, vitamin B12, and folate. Serious side effects from Injectafer arent common, but they can occur. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Possibleside effectsareweight gainand suicidal thoughts. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Injectafer can cause mild or serious side effects. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. During Injectafer treatment, your doctor will likely order blood tests. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. For example: Say you weigh 105 pounds (about 48 kilograms). And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing (A generic drug is an exact copy of the active drug in a brand-name medication.). Patients with celiac disease (gluten intolerance). People from different ethnic backgrounds process medications differently. However, side effects at the 150 mg dose may indicate that you might not . Venofer is manufactured under license from Vifor (International) Inc., Switzerland. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. During pregnancy, this medication should be used only when clearly needed. Side effects from HRT depend on a number of factors: Keep all drugs out of the reach of children and pets. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Phosphorus also helps your nerves function properly. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. These people may lose weight as their anemia improves because theyre more active. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. You may report side effects to FDA at 1-800-FDA-1088. If you have questions about side effects, call your doctor. US residents can call their local poison control center at 1-800-222-1222. Most of these side effects may go away within a few days or a couple of weeks. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. With IV infusion, the drug is given as a slow drip into your vein over a period of time. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. 2 0 obj This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Best food forward: Are algae the future of sustainable nutrition? Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Its not known if Injectafer is safe to use during pregnancy. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. experience severe side effects, please seek medical attention right away and notify the ordering physician. 2005 - 2023 WebMD LLC. Review our medical disclaimer. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. There may be drug take-back programs in your area. (For more information on Venofer, see the Injectafer vs. Venofer section above). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Talk with your doctor. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Upset stomach or throwing up. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Venofer is not for treating other forms of anemia not caused by iron deficiency. Youll receive doses of either drug by a healthcare professional at a medical facility. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. What Is the Cost of Whole Genome Sequencing (WGS)? These effects typically last between 7 and 11 hours. VenAccess is a trademark of Vifor (International) Inc. Switzerland. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Brand-name medications usually cost more than generics. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Be ready to tell or show what was taken, how much, and when it happened. Following an LSD trip, users may experience a sort of 'comedown.'. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. We cancelled my 5th because of the reaction. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It depends. You may also report side effects at https://www.fda.gov/medwatch. There have also been reports of serious allergic reactions to Venofer. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. However, many people have no side effects or only have minor side effects. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. But you kidneys need iron in order to make EPO. muscle pain. (Hemoglobin is a protein thats found in red blood cells.). Discuss the risks and benefits with your doctor. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. This site is intended for use only by US patients. Version: 7.01. Its responsible for carrying oxygen throughout your body. Many patients with kidney disease cannot get enough iron from food and require injections. Do not start, stop, or change the dose of any drug without checking with your doctor. Severeside effectsmay end up causing a lot of disruption in a persons life. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Venofer may cause significant hypotension (decreased blood pressure). Keep all regular medical and laboratory appointments. Before using, check this product visually for particles or discoloration. Does Venofer Vial interact with other medications? In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Injectafer should be stored between 68F to 77F (20C to 25C). If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. People with IDA have low blood levels of hemoglobin. Its not known how often people taking a treatment other than Injectafer had diarrhea. Pain, swelling, or redness at the injection site may occur. Infusions should be administered over at least 15 minutes. A shortage of iron can cause health problems. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Here's some detail on certain side effects this drug may cause. weakness. Call your doctor for medical advice about side effects. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually).
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